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He was too successful, however, and the Papacy found itself in the deadly embrace of the Angevins. Nicholas’ prime goal was to loosen Charles I’s grip on the Papacy, Rome, and the lands of the Church. The remaining princely family is represented by Prince Domenico Napoleone Orsini, Duke of Gravina (b. 1948). With no sons or male-line descendants, the heir to the dukedom of Gravina is his unmarried brother Don Benedetto Orsini (b. 1956), followed by his cousin Prince Lelio Orsini d'Aragona (b. 1981), whose mother is Princess Ketevan Bagration of Mukhrani.
Other distinguished family members
His first wife, Isabella Medici, being murdered, he took as his second wife Vittoria Accoramboni, widow of the murdered Francesco Peretti, a nephew of Sixtus V. Accused of murdering the latter, Paolo Giordano was obliged to leave Rome. His grandchild, (2) MATTEO ROSSO ORSINI, was made senator of Rome by Pope Gregory IX in 1241. In this capacity he took a decided stand against the ventures of Emperor Frederick II in Italy. He was a patron of religious undertakings, a personal friend of St. Francis of Assisi, and a member of that saint's Third Order. While one of the sons of Matteo Rosso, Gian Gaetano, ascended the papal throne as Nicholas III, another, (3) RINALDO, continued the activities of his father in the political field, exerting himself to the utmost to prevent the alliance of Rome with the Hohenstaufen Konradin. (13) VIRGINIO ORSINI, likewise of the ducal family of Bracciano, b.
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The second southern line
[10] Nevertheless, sources and letters suggest that there was a great deal of affection and respect between her and Lorenzo. [11] [12]Of the ten children born to them, four died in infancy. Clarice Orsini (1453–1488)[1] was the daughter of Jacopo Orsini, and his wife and cousin Maddalena Orsini both from the Orsini family, a great Roman noble house [2] and was the wife of Lorenzo de' Medici. (1) ORSO DI BOBONE, nephew of Pope Celestine III (1191-8) and the first Orsini to hold a conspicuous place in Rome. Under the protection of his uncle, the pope, he was destined to have the principal part in laying the foundation of the dominion, power, and prestige of the Roman Orsini. This branch of the family moved to Rome in the 18th century, where Duke Domenico (November 23, 1790 – April 28, 1874), married Maria Luisa Torlonia in 1823.
Orsini cardinals
The fourth duke, Francesco, was part of a conspiracy along with his brothers Giulio and Paolo against Cesare Borgia but were found out, and Francesco was strangled to death on 18 January 1503 along with his brother Paolo. One of Francesco's nephews, Flavio Orsini, was created cardinal in 1565. The fifth duke, Ferdinando (died December 6, 1549), had all his fiefs confiscated by the Spaniards, but he regained them after a 40,000 scudi payment. The line of Gravina, from the name of the eponymous city in Apulia, is the only existing line of the Orsini.
In 1850, he was Minister of War and General Lieutenant of the Papal Armies, and also Senator of Rome.
Pope Nicholas III 23rd Great Grand Uncle

They first became important in the late 12th century with the election of Giacinto Orsini as Pope Celestine III (1191–98), whose generosity to his nephews founded the territorial fortunes of the family. An accomplished condottiero, he was however also a ruthless figure who had his wife Isabella de' Medici murdered. He was succeeded by Virginio, whose heir Paolo Giordano II married the princess of Piombino and was created Prince of the Holy Roman Empire. His brother Alessandro was cardinal and Papal legate, and another brother, Ferdinando (died March 4, 1660) acquired the assets of the other line of San Gemini. In the 17th century the Dukes of Bracciano moved their residence to Rome.
(3) GIAN GAETANO ORSINI, prothonotary Apostolic, raised to the cardinalate by Pope John XXII in December, 1316; d. In 1326 he was sent to Italy as papal legate for certain lands belonging to the Papal States, and remained there until 1334. After the departure of the excommunicated emperor, the legate entered Rome with the army of King Robert of Naples, whereupon the people once more agreed to recognize the suzerainty of the pope. John XXII, however, refused to sanction the war undertaken by the cardinal legate against the Colonna, and ordered him to return to Tuscany. In November, 1328, he opened a campaign against the cities of Corneto and Viterbo, which submitted to the pope in the following year. Napoleone, another son of Matteo Rosso the Great, received Bracciano, Nerola and other lands in what is now northern Lazio.
Clarice Orsini
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Researching Italian Ancestors
Currently Ron is involved in RJ Hilton Marketing focuses on International Real Estate Development and Music Management, Hospitality. If you hear Lorenzo blamed for not being present at the death of his wife, excuse him. It seemed necessary...that he brought water from the Villa; and no one thought that she would die so soon.
(1) MATTEO ROSSO ORSINI, nephew of Cardinal Gaetano Orsini (later Pope Nicholas III), created a cardinal by Urban IV in December, 1262; d. As legate for the provinces of the Patrimony of Peter and of the Marches, he fought against Peter de Vico, who, in the name of Manfred, invaded the papal territory with German mercenaries. Soon after the elevation of his uncle, Nicholas III, to the papal throne (1277), he was named by this pope archpriest of the Vatican Basilica, rector of the great Hospital of the Holy Ghost in Vatican territory, and cardinal protector of the Franciscan Order. After the death of Nicholas III (1280), the cardinals assembled in Viterbo for the election of his successor, but, owing to party dissensions, many months passed before a decision was reached. The party which inclined towards the French, and which had the support of Charles of Anjou, King of Naples, himself present in Viterbo, wished to elect an exponent of the policy of France, and chose as their candidate the French Cardinal Simon.
In the second quarter of the 13th century, they were threatened by the expansionist policies of the Emperor Frederick II, who aimed to unite his inheritance in the south (Sicily and southern Italy) with his acquisition of the German Empire in northern Italy. He spent a great deal of time and energy attempting to gain control over Lombardy and Tuscany, which brought him into direct conflict with the Papacy. Frederick was repeatedly excommunicated by one pope after another. In order to drive off the Hohenstaufen, the Papacy contrived a deal with the brother of Louis IX of France, Charles of Anjou, Count of Provence, who was invited to Italy to assume the crown of Sicily and be a counterweight against the Empire.
L'Idole (R. Merle) also has Paolo and Lodovico Orsini as main protagonists, since the book is about Vittoria Accoramboni's life. This line was founded by Rinaldo, third son of Matteo Rosso the Great. His son, Napoleone, became a cardinal in 1288 and remained a prominent member of the Curia until his death at Avignon in 1342.
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